Status check, October 2026: the Metaculus question this resolves on now has a community median of August 2030 (range mid-2028 to 2033, 20 forecasters), which is after this market's 1 January 2030 cutoff, while this market sits at 59%. Altos hired Joan Mannick as Chief Medical Officer in August 2025, its first clinical leader, but no Altos-sponsored study is listed on ClinicalTrials.gov as of today. The first partial-reprogramming therapy to reach people is Life Biosciences' ER-100, first dosed in June 2026 for glaucoma and NAION under an IND cleared in January 2026, a disease indication rather than an aging one. For comparison, the only regulator that has accepted lifespan extension as an indication did so for dog drugs (mine): /w0lph/which-species-will-get-the-first-re
Will Altos Labs trial an anti-aging intervention in humans by 2030?
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Ṁ1kṀ9982030
59%
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This resolves to "YES" if this Metaculus question https://www.metaculus.com/questions/9592/altos-labs-trials-an-anti-aging-intervention/ resolves to a date before January 1st, 2030 UTC.
This question is managed and resolved by Manifold.
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Will a human anti-aging drug trial with mortality or lifespan as primary endpoint be registered before 2030?
23% chance
By 2060, will there be a cure to aging?
50% chance
Will a human-proven cure for aging that increases life expectancy by at least 20 years exist by 2036?
20% chance
Will we get conclusive evidence to prove that ALTO-100 performs better than placebo against Depression and/or PTSD before 2027?
15% chance
By 2030, will any treatment be shown to increase human lifespan in a randomized controlled trial?
Will a senolytic drug be used clinically to slow, prevent, or reverse aging by the end of 2033?
46% chance
Will any company successfully develop a therapeutic treatment that rejuvenates healthspan by at least 10 years by 2030?
35% chance
Will anti-aging treatments developed, approved and available for public usage by 2040?
38% chance
If a treatment is shown to increase human lifespan in a randomized controlled trial by 2030, what was the treatment?
Will a therapy that substantially slows down or reverses the aging process in humans be developed before 2040?
60% chance