Will cevumeran start a Phase III trial for pancreatic cancer by 2030? | Manifold

Will cevumeran start a Phase III trial for pancreatic cancer by 2030?

Medicine•Biology

2

9

Ṁ12

Ṁ70

2030

57%

chance

1D

1W

1M

ALL

A phase I trial of cevumeran in pancreatic cancer had some pretty [impressive results](https://www.nature.com/articles/s41586-023-06063-y). By 2030 will cevumeran (in combination with other drugs or not) enter a Phase III trial at least partially targeting pancreatic ductal adenocarcinoma?

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer - Nature

A phase I clinical trial of an adjuvant personalized mRNA neoantigen vaccine, autogene cevumeran, in patients with pancreatic ductal carcinoma demonstrates that the vaccine can induce T cell activity that may correlate with delayed recurrence of disease.

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