In order to qualify, it must:

• Have been designed on an intellectual level, with humans understanding how it works. (A mother having a baby doesn't count.)

• Clearly be an entirely new human creation, not a modified natural thing. Taking inspiration from nature is ok. (Genetically engineering an existing bacterium to do something slightly different doesn't count, but it's ok if the new life form uses DNA, has ribosomes, runs on ATP, etc.)

• Self-replicate physically, not just informatically. (Computer viruses don't count.)

• Self-replicate in a "normal" environment, not one specifically seeded with items to make it easy. (Xenobots don't count.)

• Be able to self-replicate indefinitely. If the copy it makes cannot itself make a copy, that doesn't count.

• Not be destroyed in the process.

Any instance counts, even if it occurred prior to market creation.