"Catastrophic": doesn't have to primarily impact humans, but must semi-permanently change some part of the world as we know it.
"Cascading": must trigger secondary disaster(s) or have significant indirect effects.
"Natural": the inciting event is not directly done by human actions or technology (e.g., AI, nukes), but can be triggered by anthropogenic effects (e.g., climate change).
"Disaster": must have a primarily negative outcome (loss of life, ecological damage, societal collapse, etc.).
Examples that would qualify for YES:
Temperature anomaly in the antarctic causes shelf detachment and global sea level rises, causing mass population displacement.
Complete collapse of an ecosystem (acidification finishes Great Barrier Reef die out, geological disaster causes widespread Amazon Basin toxification, etc.).
Wildfires wipe out a major world city.
The Tohoku earthquake of 2011 that caused the nuclear plant disaster in Fukushima would qualify if it happened today.
Examples that WOULDN'T trigger a YES resolution:
AI wipes out all life
A volcano creates a new island
Orcas destroy all boat rudders on the planet