Which intervention will add the most years of life to healthy people in 5 years of research?
11
Never closes
Telomere extending therapies
Stem cell therapies
Somatic reprogramming
Sirtuin targeting therapies
Senolytics
Rapamycin supplementation
Plasma/blood based therapies
Organ replacement
NAD targeting therapies
Microbiome replacement
Genetic medicine
Calorie restriction

Hat tip to Longevity Bottlenecks study: https://www.biorxiv.org/content/10.1101/2023.08.18.553936v1.full.pdf


The market assumes the same criteria as the study, e.g.:

Assumes current bottlenecks are largely cleared (e.g. biomarker validation, overall lack of funding, slow and expensive models, lack of regulatory path, etc as described in the study).

Generally healthy: non-smoking, non-obese, non-substance abusing without major infectious diseases.

Disclaimers:

  1. This question is part of Foresight’s 2023 Vision Weekends to help spark discussion amongst participants, so the phrasing and resolution criteria may be vaguer than I would normally like for this site. Apologies for that. We thought it would still be useful to make the market public to potentially inform other discussions.

  2. If you would to add alternative answers, please do so in the comments!

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