Will there be a genetic engineering method capable of changing an adult's chromosomal sex by 2100?
10
75
210
2100
48%
chance

Most cells' karyotypes (excluding neuronal cells) would have to be changeable from XX to XY or vice versa after any required amount of time, as long as it lies within the human lifespan of that time.

If only one way is achieved, the market resolves 50%.

If it is achieved only for a non-human mammal, the market resolves 20% (resp. 10%).

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Exists in a bleeding-edge experiment done once, or actually available for people to use?

bought Ṁ25 of NO

God, I wish. Betting NO as insurance.