Marco Rubio, presently a Senator from Florida, was selected by Trump to become his Secretary of State (if that falls through and Rubio keeps his seat this resolves N/A). Governor Ron Desantis will then have the power to appoint a replacement to serve for 2 years, followed by a special election to fill the seat.

Desantis himself is term limited as governor and his term ends in 2026. Previous governor Rick Scott ran for Senate after hitting his own term limit and very possibly Desantis would like to do the same with this now vacated seat (there are only two senators per state and Rick Scott is still serving so that seat is not available)

The initial options for this market were taken from this news article here, which is well worth reading: See https://www.cbsnews.com/amp/miami/news/ron-desantis-decides-rubio-senate-replacement-presidential-cabinet/

Possible clarification from creator (AI generated): If DeSantis resigns as governor before making the Senate appointment and Lt Gov Nunez makes the appointment instead, the market will continue normally and resolve based on who is appointed (rather than resolving N/A).