https://en.wikipedia.org/wiki/Church%E2%80%93Turing%E2%80%93Deutsch_principle

Resolves once there's a complete consensus among philosophers, physicists, and computer scientists, akin to the current consensus that free energy is impossible under known physics. Probably this won't happen until we have a Theory of Everything and the ability to perform experiments using exotic physics like black hole hypercomputation.

This market cares only about physics questions that could actually in principle occur. Not hypothetical questions like "what would happen if we had negative matter". (Unless it turns out there is some way to create negative matter.)