I think "cure" needs a tighter definition than is given. There are at least three different things that arguably could be called a cure. Which ones would resolve YES?

1. If autoimmune activity is detected early, intervene and prevent the pancreas from being destroyed. Two subcategories: a) requires lifelong treatment, i.e. a targetted immunosuppressant drug, or b) one-time treatment that permanently alters the patients immunresponse, i.e. a sort of reverse-vaccine.

2. Gene-therapy that prevents offspring from inheriting an increased likelihood for the disease.

3. Reversal of disease symptoms for patients who have already had significant pancreatic damage. Subcategories: a) an implanted "artificial pancrease" that lasts for multiple years (if yes, what characteristics must distinguish it from a traditional implanted insulin pump?), or b) transplanted organ from human or non-human donor, including things like regrowing from patient's own stem cells.

4. Other. Catch all for stuff I haven't thought of.

I know some people with Type I Diabetes, so I've thought about this topic a little, but my field is neither biology nor medicine.

@DanHomerick i have no expertise here, i am defining cure as a layman, so whichever you think is best i guess

@DanHomerick might need to add 'as defined by manifold' and resolve it by poll when the time comes