This would incentivize users to spend more of their free mana betting in competitive markets—likely favoring longer-term markets to reduce risk. That’s a positive outcome, as it helps reduce favourability towards short-cycle and improves overall market accuracy. It would also gradually clean up inactive legacy accounts by putting idle balances to use. And if users still choose to hold large amounts of mana, overall liquidity increases anyway—which is also a good thing.
It's a terrible idea. Forced engagement is never going to be a good thing. Having to constantly look around for markets to put your mana in, instead of investing your mana how and when you naturally want to, would make Manifold feel like a chore rather than a fun game. A lot of casual users would just quit instead of jumping through that hoop, so it would probably decrease user activity and market liquidity rather than increasing it.