I struggle to imagine which Nobel Prize categories "for the creation of the shoggoth meme" could even fit into... it would probably have to be either Peace (if the meme somehow prevents an AI-fueled World War III or something of that sort) or Literature (if Tetraspace's shoggoth tweets are somehow thought to be of the same caliber as major book-length novels, which also seems extremely unlikely).

Is there not a rule that Nobel prizes can't be awarded posthumously? Seems like Nobel prizes ceasing to exist isn't the only way the market could resolve NO.

(Having said that, I don't know Tetraspace. They could be an immortal being for all I know.)