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MANIFOLD
Full mouse connectome reconstructed by when?
6
Ṁ125Ṁ364
2055
April 30, 2051
42%
Before 2030
61%
2030-2035
10%
2035-2040
3%
2040-2045
6%
After 2045

Requires synapse and cellular connectivity mapping across one entire brain (i.e. not combining data across multiple specimens). Does not require a particular technology, e.g. could be electron microscopy or expansion microscopy based, but does require synapse-level resolution and accurate tracing of cell processes. Some degree of potential inaccuracy or very small gaps is accepted, to the same level as the adult Drosophila connectome, e.g. as described here: https://www.nature.com/articles/s41586-024-07968-y. Resolves upon publication or preprint or public announcement of completion, does not require peer reviewed publication to be accepted.

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