At least five children will be born who have undergone a genetic procedure to increase their relatedness to the original state of their tribe beyond what would be expected via normal genetics. For example a technology which would allow a native American couple each with 50% tribal blood to reliably have children with a higher percentage than the expected 50% (for example, by manipulation recombination to prefer more "original" choices)

We consider autosomal DNA only.

This includes tribes anywhere in North America.

At least five children born before Jan 1 2046

Not all tribes trate "blood quantum" as a legitimate concept but some do.

Related:

https://en.wikipedia.org/wiki/Blood_quantum_laws