This market resolves to yes if I or a commenter find at least two trustworthy publications saying that more than 100,000 human infections of H5N1 influenza in the United States. For comparison, typical flu seasons have between 10M and 40M infections. https://www.cdc.gov/flu/about/burden/index.html

The background to this question is a story about possible mammal-to-mammal transmission at a mink farm. https://www.nature.com/articles/d41586-023-00201-2

Resolution Criteria Minutia:

I am the final judge of "trustworthy." However, my judgment has not been too different from others. As a rule of thumb, and with exceptions for conflicts of interest and obvious bias, mainstream news outlets, major scientific publications, and non-partisan government agencies can put out trustworthy reports.

The multiple reports do not need to be independent. WaPo can repeat a story it got from FOX news and (assuming I believe them) that would count as "at least two"

Related:

https://manifold.markets/NathanpmYoung/will-there-be-a-pandemic-via-zoonos