Cannabinoid Hyperemesis Syndrome (CHS) is thought to be caused by an overstimulation, downregulation or both of the endocannabinoid system. Compounds such as Tetrahydrocannabinol (THC) are thought to be the primary cause of CHS due to the way they bind to receptors. Cannabidiol (CBD) is said to interact with the CB1 receptors in a less direct way and could have anti-nasua properties.

This market resolves Yes if studies prove CBD aggravates CHS symptoms. Resolves No if it's proven CBD does not cause a worsening of symptoms.