Nipah is one of the deadliest viruses in the world and considered one of the top future pandemic risks.

We're hosting a protein design competition on Proteinbase where people can design binders against the virus and we will test 1200 of those designs in our lab to see if they actually work.

How many of those 1200 proteins will actually bind to the target? Last year's EGFR competition had a 13.5% hit rate (54 out of 400 proteins) -- what will it be for Nipah virus?

The response was incredible: Over 10’000 designs were submitted, over 5 times the number of designs in the past 2 competitions combined, with more than 650 total participants.
We wrote a blog post with analysis around which protein design models were used, what types of proteins designed etc here: https://www.adaptyvbio.com/blog/nipah-submissions/

How will this be resolved?

We are publishing the lab results on Jan 18 2026. Binders are validated using SPR (Surface Plasmon Resonance) in our lab at Adaptyv Bio. All results will be open-sourced on Proteinbase.