There will be an initial cooling down period for changes to try and have this market match the spirit of the quesiton. After that period it will resolve to the description whether it matches this spirit or not, so lets attempt to get the wording right.

Current wording:

Will 1% or more of Americans purchase (either themselves or via insurance) services that claim primarily to clean their blood, before 2040. Inflation adjusted from 2024.

The spirit of the question is to figure out whether bloodcleaning services (eg for microplastics) will go mainstream, either for curing disease or broader wellbeing. I can imagine that a covid treatment could involve blood cleaning for instance.