This is Matchday 1 of the 2025–26 Serie A season, scheduled for August 23, 2025. Napoli enter as the reigning 2024–25 Serie A champions.

Resolution Criteria

• Sassuolo if Sassuolo win.

• Draw if the score is tied.

• Napoli if Napoli win.

• If the match is canceled it resolves N/A.

• If the match is postponed or administratively awarded, the market resolves to the result Lega Serie A records as the official outcome when published.