Lantern Bioworks is attempting to cure cavities via a treatment that modifies the oral microbiome; see 

<strike>If they achieve their bioengineering goal</strike> They have achieved their bioengineering goal. Will they be able to get "shots in arms" (or, uh, "bacteria in mouths") at a 10,000-person scale by 2030? (Participants treated in trials count.)

It's not clear how public this information will be, though hopefully they'll be willing to share. Resolution may be delayed. If 6+ months after close it seems like we won't get a concrete answer, may resolve to % based on my credence that this has happened. I will not bet.