Due to the loan system on manifold, it's possible to end up with a negative net worth as a result of a market going against you. We saw this happen in a big way with the Whales Vs Minnows market where 

 ended up with a net worth of around -M2,000,000.

Will this happen to the collective tune of more than M500k as a result of the markets on the replication of the supposed LK-99 superconductor?

For reference: last time I checked the mana loan system was that you get 2% of the money you invested back as a loan for every day you are invested in a market. You have to pay this off when the market resolves. As a result of this people who invest in long term markets may end up with total loans much higher than their net worth, which is a fragile situation.

The reason I'm interested in this is it somewhat undermines the manifold economy if lots of people have a hugely negative net worth, because an equal amount of positive mana has to end up somewhere and this will cause inflation. It also puts the whole manaconomy at risk if, for instance, lots of people try to donate their mana to charity at once and this costs manifold way more than the revenue they are getting from people buying mana.