Resolves yes if and only if human brains are unambiguously weaker than AI in every domain.

(At time of market creation, I expect this to resolve yes by 2024.)

This does not require AI to have replaced humans in practical tasks, only that there is at least one single integrated AI that can in fact beat us at absolutely everything.

Note: this includes understanding the human experience. An AI that passes this test would understand humans very dramatically better than most of us understand ourselves, since it'd need to be able to empathize with us across substrates.

Note #2: This is not a per-watt question. The AI is allowed to use arbitrarily much more compute than humans to do the task, as long as it can produce more accurate results than the best trained human in a given task. This will likely require the AI to be one that does active exploration. 