This question resolves to YES if there are >=84,800 confirmed cases of monkeypox worldwide by year-end, using the cumulative confirmed cases of Jan 10 2023, from Our World in Data: 

[Edit: Someone pointed out that Our World in Data would sometimes back adjust the data. I will resolve this market according to the earliest reported number of cases for Jan 10,2023. For example: if 84799 cases for Jan 10 was displayed on Jan 11, and on Jan 15 the number of cases for Jan 10 are updated to 84801, this market would still resolve to no. ]